Org 20599CAS号： 187652-71-7分子式： C25H40ClNO3分子量： 438.04描述应用纯度储存/保存方法形态别名密度熔点沸点折射率光学活性IC50可溶性/溶解性PubChem CID
| 产品描述 | |
| 描述 |
Org 20599 is a positive allosteric modulator. Direct agonist of GABAA receptors at higher concentrations. Anesthetic steroid. Shown to induce hypnosis and lost of righting reflexes in mice.
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| 应用 |
A positive allosteric modulator and agonist of GABA receptors
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| 纯度 |
≥97%
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| 储存/保存方法 |
Store at room temperature
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
(2β,3α,5α)-21-Chloro-3-hydroxy-2-(4-morpholinyl)pregnan-20-one
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| 密度 |
1.17 g/cm3 (Predicted)
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| 熔点 |
215.81° C (Predicted)
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| 沸点 |
~544.3° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.55 (Predicted)
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| 光学活性 |
α20/D +165.5°, c = 0.4 in chloroform
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| IC50 |
GABA receptors: EC5050 = 1.1 µM; glycine receptors: EC5050 = 22.9 µM
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| 可溶性/溶解性 |
Soluble in 1eq. HCl (100 mM), and DMSO (100 mM).
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| PubChem CID |
9850026
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