This peptide belongs to the functional domain of BAK, the member of the Bcl-2 family. Bak promotes apoptosis and binds anti-apoptotic family members including Bcl-2 and Bcl-xL. This domain in Bakt is necessary and sufficient for cytotoxic activity and bin

H – Ser – Thr – Met – Gly – Gln – Val – Gly – Arg – Gln – Leu – Ala – Ile – Ile – Gly – Asp – Asp – Ile – Asn – Arg – Arg – Tyr – Asp – Ser – Glu – Phe – OH

≥ 95%

-20°C

STMGQVGRQLAIIGDDINRRYDSEF

Chittenden, T. et al. EMBO J. 14, 5589 (1995).