BAY 73-1449CAS号： 693790-96-4分子式： C26H23N3O3分子量： 425.48描述储存/保存方法可溶性/溶解性靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:55 mg/ml (129.27 mM)
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| 生物活性 | |
| 靶点 |
Prostacyclin receptor:<0.1 nM
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| In vivo(体内研究) |
In male Wistar rats, BAY 73-1449 (0.1-1 mg/kg; i.v.) significantly reduced splenic shunt vessel outflow without affecting mesenteric inflow[1]. BAY 73-1449 (1-5 mg/kg; s.c.) has no effects on portal pressures and the degree of porto-systemic shunting in rats[1].
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