GM 1489CAS号： 170905-75-6分子式： C27H33N3O4 分子量： 463.57描述应用纯度储存/保存方法形态别名密度熔点沸点折射率Ki 数据可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
GM 1489 is a potent broad-range inhibitor of MMP (matrix metalloproteinases). Inhibits MMPs in vitro (Ki = 0.2 nM for MMP-1; Ki = 500 nM for MMP-2; Ki = 20 μM for MMP-3; Ki = 100 nM for MMP-8; and Ki = 100 nM for MMP-9). GM 1489 also reduces the inflammatory and the hyperproliferative responses that occur following topical phorbol ester application.
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| 应用 |
A potent broad-range inhibitor of matrix metalloproteinases
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| 纯度 |
>95%
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| 储存/保存方法 |
Store at -20° C
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
N-[(2R)-2-(Carboxymethyl)-4-methylpentanoyl]-L-tryptophan-(S)-methyl-benzylamide
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| 密度 |
1.20 g/cm3 (Predicted)
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| 熔点 |
150° C
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| 沸点 |
795.41° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.60 (Predicted)
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| Ki 数据 |
MMP-1: Ki= 0.2 nM; MMP-2: Ki= 500 nM; MMP-3: Ki= 20 µM; MMP-8: Ki= 100 nM; MMP-9: Ki= 100 nM
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| 可溶性/溶解性 |
Soluble in DMSO (25 mg/ml).
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| MDL |
MFCD02683942
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| PubChem CID |
10322165
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