ABD459

ABD459CAS号: 1047670-51-8分子式: C24H17BrCl2N2O2分子量: 516.2描述纯度储存/保存方法参考文献

产品描述
描述
ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM).1 It inhibits food consumption in nonfasted mice without affecting motor activity.1 ABD459 reduces active food seeking for 5-6 hours after treatment, with no rebound after washout. ABD459 also diminishes rapid eye movement (REM) sleep, with no alterations of wakefulness or non-REM sleep.1
纯度
≥95%
储存/保存方法
Store at -20℃
参考文献
参考文献
1.Goonawardena, A.V.,Plano, A.,Robinson, L., et al. Modulation of food consumption and sleep-wake in mice by the neutral CB1 antagonist ABD459. Behav. Pharmacol. 26(3), 289-303 (2015).

分子结构图

ABD459