AZD4573CAS号： 2057509-72-3分子式： C22H28ClN5O2分子量： 429.94描述纯度储存/保存方法别名可溶性/溶解性In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
AZD4573 is a potent and highly selective CDK9 inhibitor (IC50 of <4 nM) that enables transient target engagement for the treatment of hematologic malignancies.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
AZD-4573
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| 可溶性/溶解性 |
DMSO : 50 mg/mL (116.30 mM)
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| 生物活性 | |
| In vitro(体外研究) |
CDK93 nM (IC50)Clinical TrialStoragePowder-20°C3 years 4°C2 yearsIn solvent-80°C6 months -20°C1 monthSolvent & Solubility
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| In vivo(体内研究) |
AZD4573 exhibits a short half-life in multiple species (less than one hour in rat, dog and monkey) and good solubility for intravenous administration.
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分子结构图
