ASP2453

ASP2453CAS号: 2241719-73-1分子式: C40H48F3N7O4分子量: 747.85描述纯度储存/保存方法可溶性/溶解性靶点

产品描述
描述
ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
纯度
97%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:250 mg/mL (334.29 mM)
生物活性
靶点
KRAS G12C:40 nM (IC50)