ASP2453CAS号: 2241719-73-1分子式: C40H48F3N7O4分子量: 747.85描述纯度储存/保存方法可溶性/溶解性靶点
产品描述 | |
描述 |
ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
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纯度 |
97%
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
可溶性/溶解性 |
DMSO:250 mg/mL (334.29 mM)
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生物活性 | |
靶点 |
KRAS G12C:40 nM (IC50)
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