LY451395CAS号： 375345-95-2分子式： C21H30N2O4S2分子量： 438.6描述纯度储存/保存方法别名可溶性/溶解性靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
Mibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
LY451395
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| 可溶性/溶解性 |
DMSO : ≥ 25 mg/mL (57.00 mM)
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| 生物活性 | |
| 靶点 |
iGluR
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| In vivo(体内研究) |
Incubation of Mibampator (LY451395) with Actinoplanes missouriensis NRRL B3342 generated several metabolites that were previously detected in the in vivo metabolism studies of the preclinical species . LY404187 and Mibampator (LY451395) reverses the central effects of an acutely intoxicating dose of ethanol in the rat. Mibampator (LY451395) significantly and dose-dependently reversed ethanol-induced deficits in both motor coordination and disruptions in an operant task where animals were trained to press a lever for food reward.
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分子结构图
