CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.

98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

DMSO:250 mg/mL (514.00 mM)

Cdc42 WT, in GDP binding assay:0.3 μM (EC50), Cdc42Q61L mutant, in GDP binding assay:0.5 μM (EC50), Cdc42 WT, in GTP binding assay:1.0 μM (EC50), Cdc42Q61L mutant, in GTP binding assay:1.2 μM (EC50)