GW441756CAS号： 504433-23-2分子式： C17H13N3O分子量： 275.3描述纯度储存/保存方法别名外观可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2. |
| 纯度 |
>98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
GW 441756; GW-441756
|
| 外观 |
orange Powder
|
| 可溶性/溶解性 |
DMSO : 4.1 mg/mL (15 mM)
|
| 生物活性 | |
| 靶点 |
TrkA
|
| In vitro(体外研究) |
GW441756 can specifically block TrkA-induced cell death in a dose-dependent manner. GW441756 can block TrkA-mediated γH2AX production and apoptosis in TrkA-overexpressing cells.
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分子结构图
