Mouse anti-GJC2 Monoclonal Antibody(N-term)(391CT6.4.3)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法存储溶液研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Mouse Monoclonal Antibody (Mab)
|
| 别名 |
GJC2抗体;Gap junction gamma-2 protein; Connexin-466; Cx466; Connexin-47; Cx47; Gap junction alpha-12 protein; GJC2; GJA12
|
| 宿主 |
Mouse
|
| 特异性 |
This GJC2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GJC2.
|
| 反应种属 |
Human
|
| 应用 |
WB~~1:100~500
|
| 分子量 |
Predicted molecular weight: 47kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
391CT6.4.3
|
| 同种型 |
IgM
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 存储溶液 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
|
| 研究领域 |
Neuroscience;Signal Transduction
|
| 靶标 | |
| 背景说明 |
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems.
|
| 细胞定位 |
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
|
| UniProt |
Q5T442
|
| 参考文献 | |
| 参考文献 |
Ferrell, R.E., et al. Am. J. Hum. Genet. 86(6):943-948(2010)
Wang, J., et al. Brain Dev. 32(3):236-243(2010) Ishikawa, T., et al. Rinsho Shinkeigaku 50(1):7-11(2010) Ruf, N., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (2), 226-232 (2009) : Orthmann-Murphy, J.L., et al. Brain 132 (PT 2), 426-438 (2009) : |
实验结果图
GJC2 Antibody (N-term) (Cat. #JP100186 ) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the GJC2 antibody detected the GJC2 protein (arrow).