CGP 36216 (hydrochloride)CAS号： 1781834-71-6分子式： C5H14NO2P • HCl分子量： 187.6描述纯度储存/保存方法参考文献
| 产品描述 | |
| 描述 |
CGP 36216 is a selective antagonist of GABAB receptors (IC50 = 43 µM).1,2 Its action is reversed by the GABAB receptor agonist baclofen.2 It is active at presynaptic, but not postsynaptic, receptors.2
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| 纯度 |
≥98%
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| 储存/保存方法 |
Store at -20℃
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| 参考文献 | |
| 参考文献 |
1.Froestl, W.,Mickel, S.J.,von Sprecher, G., et al. Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists. Journal of Medicinal Chemistry 38, 3313-3331 (1995).
2.Ong, J.,Bexis, S.,Marino, V., et al. CGP 36216 is a selective antagonist at GABAB presynaptic receptors in rat brain. European Journal of Pharmacology 415, 191-195 (2001). |
分子结构图
