AS-8351CAS号： 796-42-9分子式： C17H13N3O2分子量： 291.3描述纯度储存/保存方法别名外观靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
AS 8351 induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409. |
| 纯度 |
>98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
AS8351,AS 8351，NSC51355，NSC 51355，NSC-51355
|
| 外观 |
Powder
|
| 生物活性 | |
| 靶点 |
Histone Demethylase
|
| In vitro(体外研究) |
AS8351 affects epigenetic modifications by competing with α-ketoglutarate (α-KG) for chelating iron in certain epigenetic enzymes, such as the JmjC domain-containing histone demethylases (JmjC-KDMs) that require α-KG and iron as co-factors.
|
分子结构图
