HJC0350

HJC0350CAS号: 885434-70-8分子式: C15H19NO2S分子量: 277.38描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)参考文献

产品描述
描述
HJC0350 is a potent and selective EPAC2 inhibitor with IC50 of 0.3 μM, exhibiting no inhibition on Epac1.
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:52 mg/mL warmed (187.46 mM)
生物活性
靶点
EPAC2
In vitro(体外研究)
HJC0350 selectively blocks cAMP-induced EPAC2 activation but do not inhibit cAMP-mediated PKA activation. In HEK293/EPAC2-FL cells, HJC0350 also inhibits 007-AM mediated cellular activation of EPAC2.
参考文献
参考文献
  • 1. Chen H, et al. J Med Chem. 2013, 56(3), 952-962.
  • 分子结构图

    HJC0350