Mouse anti-RRAS2 Monoclonal Antibody(1578CT130.349.47.14)描述别名宿主特异性反应种属预测反应种属应用分子量类型克隆号同种型储存/保存方法研究领域背景说明细胞定位UniProt参考文献
概述 | |
描述 |
Purified Mouse Monoclonal Antibody (Mab)
|
别名 |
RRAS2抗体;Ras-related protein R-Ras2; Ras-like protein TC21; Teratocarcinoma oncogene; RRAS2; TC21
|
宿主 |
Mouse
|
特异性 |
This RRAS2 antibody is generated from a mouse immunized with a recombinant protein of human RRAS2.
|
反应种属 |
Human, Mouse
|
预测反应种属 |
M
|
应用 |
WB~~1:4000
|
分子量 |
Predicted molecular weight: 23kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
性能 | |
类型 |
Monoclonal Antibody
|
克隆号 |
1578CT130.349.47.14
|
同种型 |
IgG1,k
|
储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
研究领域 |
Cancer;Signal Transduction
|
靶标 | |
背景说明 |
It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
|
细胞定位 |
Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS)
|
UniProt |
P62070
|
参考文献 | |
参考文献 |
Drivas G.T.,et al.Mol. Cell. Biol. 10:1793-1798(1990).
Chan A.M.-L.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:7558-7562(1994). Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Taylor T.D.,et al.Nature 440:497-500(2006). |
实验结果图
All lanes : Anti-RRAS2 Antibody at 1:4000 dilution Lane 1: A431 whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 23 kDa Blocking/Dilution buffer: 5% NFDM/TBST.