CGP-53353

CGP-53353CAS号: 145915-60-2分子式: C20H13F2N3O2分子量: 365.33描述应用纯度储存/保存方法别名外观密度熔点沸点折射率PK值可溶性/溶解性MDLPubChem CID

产品描述
描述
CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients.
应用
A highly selective PKCβII inhibitor
纯度
≥98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
别名
DAPH-7
外观
orange solid
密度
1.47 g/cm3
熔点
273.71° C
沸点
630.82° C (Predicted)
折射率
n20D 1.70
PK值
pKa: 8.95, pKb: 0.53
可溶性/溶解性
DMSO : ≥ 50 mg/mL (136.86 mM)
MDL
MFCD00938569
PubChem CID
6711154

分子结构图

CGP-53353