BDP-13176

BDP-13176CAS号: 2290660-61-4分子式: C24H22Cl2N6O2分子量: 497.38描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)

产品描述
描述
BDP-13176 is a potent inhibitor of fascin 1(Kd of 90 nM and an IC50 of 240 nM). It has potential as an anti-metastatic agent
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:125 mg/mL (251.32 mM)
生物活性
靶点
fascin 1:240 nM, fascin 1:90 nM(Kd)
In vitro(体外研究)
BDP-13176 (0-1 μM) inhibits fascin 1 bundling activity. Fascin is an actin binding and bundling protein that is not expressed in normal epithelial tissues but overexpressed in a variety of invasive epithelial tumors. It has a critical role in Cancer cell metastasis by promoting cell migration and invasion.