BDP-13176CAS号: 2290660-61-4分子式: C24H22Cl2N6O2分子量: 497.38描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)
产品描述 | |
描述 |
BDP-13176 is a potent inhibitor of fascin 1(Kd of 90 nM and an IC50 of 240 nM). It has potential as an anti-metastatic agent
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纯度 |
98%
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
可溶性/溶解性 |
DMSO:125 mg/mL (251.32 mM)
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生物活性 | |
靶点 |
fascin 1:240 nM, fascin 1:90 nM(Kd)
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In vitro(体外研究) |
BDP-13176 (0-1 μM) inhibits fascin 1 bundling activity. Fascin is an actin binding and bundling protein that is not expressed in normal epithelial tissues but overexpressed in a variety of invasive epithelial tumors. It has a critical role in Cancer cell metastasis by promoting cell migration and invasion.
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