CP-31398 diHydrochlorideCAS号: 1217195-61-3分子式: C22H28Cl2N4O分子量: 435.4描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)
产品描述 | |
描述 |
CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53.
|
纯度 |
98%
|
储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
|
基本信息 | |
可溶性/溶解性 |
DMSO:6 mg/ml (13.78 mM)
|
生物活性 | |
In vitro(体外研究) |
CP-31398 (15 μg/mL, 20 hours) could induce apoptosis and cell cycle arrest in SW480 cells[1]. CP-31398 (36.75 μM, 16 h) induces p21 in p53-mutant cells[2].
|