L189CAS号： 64232-83-3分子式： C11H10N4OS分子量： 246.29描述纯度储存/保存方法外观折射率IC50Ki 数据可溶性/溶解性PubChem CID
| 产品描述 | |
| 描述 |
L189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 μM respectively) that blocks DNA binding (Ki = 5 μM for DNA ligase I). Shown to preferentially inhibits step 2 of the ligation reaction, and inhibits base excision repair (BER) and non-homologous end joining (NHEJ).
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 外观 |
Light yellow to yellow solid
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| 折射率 |
n20D ~1.73 (Predicted)
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| IC50 |
DNA ligase I: IC50 = 5 µM; DNA ligase III : IC50 = 9 µM; DNA ligase IV : IC50 = 5 µM
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| Ki 数据 |
DNA ligase I: Ki= 5 µM
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| 可溶性/溶解性 |
DMSO : 25 mg/mL
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| PubChem CID |
824710
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分子结构图
