Potent and selective IKKβ inhibitor

>98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

8-(2-((3S,4S)-3,4-bis(hydroxymethyl)-3,4-dimethylpyrrolidin-1-yl)-5-chloroisonicotinamido)-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide

Off-white solid

DMSO ：61.91 mg/mL

A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924.
Toth JI,et al. Cell Rep. 2012 Apr 19;1(4):309-16. PMID: 22832224.
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