Rabbit anti-Laminin Recombinant Monoclonal Antibody(148-42)别名宿主反应种属应用免疫原形式浓度纯化方法类型克隆号储存/保存方法存储溶液背景说明
概述 | |
别名 |
LN; Laminins
|
宿主 |
Rabbit
|
反应种属 |
Human
|
应用 |
Sandwich ELSIA
|
免疫原 |
Recombinant protein
|
性能 | |
形式 |
Liquid
|
浓度 |
2 mg/mL
|
纯化方法 |
Protein A affinity column
|
类型 |
Monoclonal Antibody
|
克隆号 |
148-42
|
储存/保存方法 |
Store at 4℃ for one year.
|
存储溶液 |
PBS pH7.4, 0.03% Proclin 300
|
靶标 | |
背景说明 |
Laminins are heterotrimeric proteins with a high molecular mass (~400 to ~900 kDa). They contain three different chains (α, β and γ) encoded by five, four, and three paralogous genes in humans, respectively. Laminins are heterotrimeric proteins with a high molecular mass (~400 to ~900 kDa). They contain three different chains (α, β and γ) encoded by five, four, and three paralogous genes in humans, respectively. The trimeric proteins intersect to form a cross-like structure that can bind to other cell membrane and extracellular matrix molecules. The three shorter arms are particularly good at binding to other laminin molecules, which allows them to form sheets. The long arm is capable of binding to cells, which helps anchor organized tissue cells to the basement membrane. Laminin is positively correlated with the degree of liver fibrosis activity, which is significantly increased in chronic active hepatitis, cirrhosis and primary liver cancer. Laminin can also reflect the progression and severity of liver fibrosis.
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实验结果图