MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection, diagnosis, and study of cancer.MHI-148 is taken up and accumulates in the lysosomes and mitochondria of tumor cells but is not taken up in the lysosomes and mitochondria of normal cells.MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection and diagnosis of cancer.

96%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

DMSO:18.7 mg/mL (24.5 mM)

Compound MHI-148 (10 µM; 1 h) demonstrates notably higher JPorption in HT-29 colon carcinoma cells compared to normal NIH3T3 fibroblasts.[1] alongside its capacity for tumor imaging and targeted properties.[1]
Compound MHI-148 (0-1.5 µM; 3 days) exhibits only negligible toxicity in both HT-29 and NIH3T3 cells.[1]