Rabbit anti-CD81 Recombinant Monoclonal Antibody(144-22)描述别名宿主特异性反应种属预测反应种属应用免疫原形式浓度纯化方法类型克隆号储存/保存方法存储溶液背景说明组织特异性翻译后修饰细胞定位UniProt
概述 | |
描述 |
May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May acts a the viral receptor for HCV
|
别名 |
CD81抗体;CD81 antigen; TAPA-1; Tspan-28
|
宿主 |
Rabbit
|
特异性 |
CD81 antibody detects endogenous levels of total CD81.
|
反应种属 |
Human, Mouse
|
预测反应种属 |
Horse
|
应用 |
IHC-P: 1:200
|
免疫原 |
Recombinant protein
|
性能 | |
形式 |
Liquid
|
浓度 |
0.5 mg/ml
|
纯化方法 |
Protein A affinity column
|
类型 |
Monoclonal Antibody
|
克隆号 |
144-22
|
储存/保存方法 |
Store at -20℃ for one year.
|
存储溶液 |
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
|
靶标 | |
背景说明 |
CD81 (encoded by the CD81 gene) deficiency is a human autosomal recessive disorder also resulting in hypogammaglobulinemia. CD81 is a tetraspanin molecule expressed on immune cells, hepatocytes, and most stromal and epithelial cells, unlike CD19 and CD21 which are mostly expressed on B cells.
|
组织特异性 |
Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
|
翻译后修饰 |
Not glycosylated.
|
细胞定位 |
Cell Membrane
|
UniProt |
P60033
|
实验结果图
IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD81 antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human liver. Anti-CD81 antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human cerebral cortex. Anti-CD81 antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human ovarian cancer. Anti-CD81 antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human diffuse large B-cell lymphoma. Anti-CD81 antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded mouse cerebral cortex. Anti-CD81 antibody was used at 1/200 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.