MDL 105,212 hydrochlorideCAS号： 167261-59-8分子式： C34H39Cl2N3O5•HCl分子量： 677.06描述应用储存/保存方法形态别名折射率IC50Ki 数据可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
MDL 105,212 hydrochloride is a non-peptide tachykinin antagonist that has high affinity for NK1 and NK2 receptors.
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| 应用 |
A non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors.
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| 储存/保存方法 |
Store at 4° C
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
1-[2-[(3R)-3-(3,4-dichlorophenyl)-1-(3,4,5-trimethoxybenzoyl)pyrrolidin-3-yl]ethyl]-4-phenylpiperidine-4-carboxamide hydrochloride
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| 折射率 |
n20D 1.59 (Predicted)
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| IC50 |
NK-1R: IC50 = 3 nM (human); Histamine H1 Receptor: IC50 = 3 nM (human); NK-2R: IC50 = 8 nM (human)
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| Ki 数据 |
NK-2R: Ki= 1 nM (human); NK-1R: Ki= 3 nM (human); NK-3R: Ki= 0.2 µM (human)
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| 可溶性/溶解性 |
Soluble in water.
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| MDL |
MFCD01861939
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| PubChem CID |
153995
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