(R)-(+)-HA-966CAS号： 123931-04-4分子式： C4H8N2O2分子量： 116.12描述应用纯度储存/保存方法形态别名外观光学活性IC50PK值Ki 数据可溶性/溶解性
| 产品描述 | |
| 描述 |
(R)-(+)-HA-966 has been reported to be a cell permeable antagonist and a partial agonist at the glycine site of the NMDA receptor. (R)-(+)-HA-966 is an inhibitor of NMDA and an activator of NMDA. |
| 应用 |
An antagonist/partial agonist at the glycine site of the NMDA receptor
|
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
R(+)-3-Amino-1-hydroxy-2-pyrrolidinone
|
| 外观 |
White solid
|
| 光学活性 |
α20/D +112.2°, c = 1 in water; α22/D +103°, c = 1 in water
|
| IC50 |
Glutamate NMDA receptor: IC50 = 12.5 µM (rat); Glutamate receptor subunit ζ 1: IC50 = 12.5 µM (rat)
|
| PK值 |
pKa: 7.19 (Predicted)
|
| Ki 数据 |
Rat: Ki= 2.5 µM; Glutamate receptor subunit ε 3: Ki= 2.5 µM (rat)
|
| 可溶性/溶解性 |
Soluble in water (100 mM)
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分子结构图
