Tyrphostin AG 957CAS号： 140674-76-6分子式： C15H15NO4分子量： 273.28描述纯度储存/保存方法别名外观可溶性/溶解性
| 产品描述 | |
| 描述 |
Tyrphostin AG 957 is a potent tyrosine kinase inhibitor. Selectively blocks the tyrosine kinase activity of human p210bcr-abl (Ki = 750 nM) over p140c-abl (Ki = 10 μM). Also decreases p210bcr-abl phosphorylation in viable K562 cells at concentrations and durations of exposure that also inhibit cell proliferation. Reported to alter the physical state of p210bcr-abl and the association of p210bcr-abl with Shc and Grb2 in K562 cells. |
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
AG 957；AG957；NSC 654705
|
| 外观 |
Off-white to pink-brown solid.
|
| 可溶性/溶解性 |
Soluble in DMSO (5 mg/ml), acetone, and ethyl acetate. Insoluble in dichloromethane.
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分子结构图
