Nsc 109555CAS号： 15427-93-7分子式： C19H24N10O•2C7H8O3S分子量： 752.86描述应用储存/保存方法形态IC50可溶性/溶解性PubChem CID
| 产品描述 | |
| 描述 |
NSC 109555 ditosylate is an ATP-competitive reversible Chk2 (checkpoint kinase 2) inhibitor that displays no effect on a range of other kinases, including Chk1. NSC 109555 ditosylate inhibits H1 phosphorylation as well as attenuates mitochondrial ATP synthesis.
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| 应用 |
A reversible ATP-competitive Chk2 inhibitor
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| 储存/保存方法 |
Store at -20° C
|
| 形态 |
Solid
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| 基本信息 | |
| IC50 |
ATP-competitive Chk2: IC50 = 0.2 µM; histone H1 phosphorylation: IC50 = 0.24 µM; Chk1: IC50 = >10 µM
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| 可溶性/溶解性 |
Soluble to 10 mM in DMSO
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| PubChem CID |
12449850
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