AY 9944 dihydrochlorideCAS号： 366-93-8分子式： C22H28Cl2N2•2HCl分子量： 464.30描述纯度储存/保存方法形态别名IC50可溶性/溶解性
| 产品描述 | |
| 描述 |
AY 9944 is an inhibitor of hedgehog (Hh) signaling, possibly via several mechanisms. AY 9944 inhibits DHCR7 (Δ7-dehydrocholesterol reductase) (IC50 = 13 nM), thus reducing cholesterol biosynthesis, and also inhibiting cholesterol esterification. AY 9944 may also directly block the cellular response to hedgehog proteins. AY 9944 is an inhibitor of EBP. |
| 纯度 |
≥98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride
|
| IC50 |
DHCR7: IC50 = 13 nM
|
| 可溶性/溶解性 |
Soluble in water (50 mM), and DMSO (14 mg/ml).
|
分子结构图
