AZD9898

AZD9898CAS号: 2042347-69-1分子式: C20H19ClF3N3O4分子量: 457.83描述纯度储存/保存方法可溶性/溶解性靶点In vivo(体内研究)

产品描述
描述
AZD9898 is an inhibitor of leukotriene-C4 synthetase with an IC50 of 0.28 nM. AZD9898 can be used in studies about asthma. AZD9898 mitigates the GABA binding and hepatic toxicity signal.
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:225mg/mL (491.4mM)
生物活性
靶点
LTC4S:0.28 nM
In vivo(体内研究)
AZD9898 (10 and 100 mg/kg; oral) is well tolerated and shows no safety concerns[1].