WZ811CAS号: 55778-02-4分子式: C18H18N4分子量: 290.36描述纯度储存/保存方法别名可溶性/溶解性靶点In vitro(体外研究)
产品描述 | |
描述 |
WZ811 is a novel small molecular and potency CXCR4 antagonist with EC50 of 0.3 nM. |
纯度 |
98% min
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
别名 |
WZ-811; WZ 811
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可溶性/溶解性 |
DMSO Solubility: 30 mg/mL (103.32 mM)
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生物活性 | |
靶点 |
CXCR4
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In vitro(体外研究) |
WZ811 is a highly potent competitive antagonist of CXCR4. WZ811 is effective in counteracting SDF-1 on cAMP reduction at doses as low as a few nanomoles. WZ811 blocks SDF-1-mediated invasion with EC50 of 5.2 nM.
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分子结构图