NE 10790CAS号： 152831-36-2分子式： C8H10NO6P分子量： 247.14描述纯度储存/保存方法别名可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
NE 10790, a poor farnesyl pyrophosphate synthase inhibitor, is a phosphonocarboxylate analogue of the potent bisphosphonate risedronate and is a weak antiresorptive agent.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
3-PEHPC
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| 可溶性/溶解性 |
H2O : 5 mg/mL (20.23 mM; ultrasonic and adjust pH to 6 with NaOH)
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| 生物活性 | |
| 靶点 |
FPP synthase.
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| In vitro(体外研究) |
NE 10790 inhibits incorporation of [14C]mevalonic acid into Rab6, but not into H-Ras or Rap1, proteins that are modified by FTase and GGTase I, respectively. NE 10790 reduces viability in J774 cells. NE 10790 prevents prenylation of 22-26-kDa proteins that are not modified by FTase or GGTase I.
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分子结构图
