BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).

98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

DMSO:45.0 mg/mL (128.1 mM)

RARα:2 nM (Ki)

In WT cells, BMS 753 can reduce RAR β Transcription level of 2 in a dose dependent mode. At RAR γ-/- cells, 100 nM of BMS 753 efficiently induces RAR β 2 Transcription. In contrast, in RAR α-/- In cells, up to 100 nM of BMS 753 can not activate RAR β 2[1].