ARL-17477 dihydrochloride hydrateCAS号： 866914-87-6(anhydrous)分子式： C20H20ClN3S•2HCl分子量： 442.83描述应用储存/保存方法形态别名IC50可溶性/溶解性MDL
| 产品描述 | |
| 描述 |
ARL-17477 dihydrochloride may be used in cell signaling studies. ARL-17477 is an nNOS specific inhibitor. The IC50 against rat nNOS is 35 nM and it has 100-fold selectivity over endothelial and inducible isoforms. ARL-17477 penetrates the brain, and reduces infarct size and reduces cerebral blood flow in several different rodent models of ischemic brain injury.
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| 应用 |
A nNOS inhibitor
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| 储存/保存方法 |
Store at 4° C
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
N-[4-[2-[[(3-chlorophenyl)methyl]amino]ethyl]phenyl]-2-thiophenecarboximidamide dihydrochloride
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| IC50 |
nNOS: IC50 = 35 nM (rat)
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| 可溶性/溶解性 |
Soluble in water (≥5 mg/ml).
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| MDL |
MFCD21608518
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