ABBV-744CAS号： 2138861-99-9分子式： C28H30FN3O4分子量： 491.55描述纯度储存/保存方法可溶性/溶解性靶点
| 产品描述 | |
| 描述 |
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:45 mg/mL (91.54 mM)
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| 生物活性 | |
| 靶点 |
BRD2 (BD2):8 nM (IC50), BRD4 (BD2):3 nM (Kd), BRD4 (BD2):4 nM (IC50), BRD3 (BD2):13 nM (IC50), BRDT (BD2):18 nM (IC50)
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