NEO2734CAS号： 2081072-29-7分子式： C22H24F3N3O3分子量： 435.44描述纯度储存/保存方法别名可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nm for both p300> |
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
EP31670
|
| 可溶性/溶解性 |
DMSO : 27.5 mg/mL (63.15 mM)
|
| 生物活性 | |
| 靶点 |
CBP/p300
|
| In vitro(体外研究) |
NEO2734, a novel dual inhibitor of BET and CBP/p300, is active in both hotspot mutant (F133V) and non-hotspot mutant (Q165P) PCa cells in vitro and in vivo.
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分子结构图
