GSK837149ACAS号： 13616-29-0分子式： C23H22N8O5S2分子量： 554.6描述纯度储存/保存方法参考文献
| 产品描述 | |
| 描述 |
A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). GSK837149A is a selective, reversible inhibitor of FAS (pIC50 = 7.8).1 It acts by inhibiting the β-ketoacyl reductase activity of FAS.
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| 纯度 |
≥95%
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| 储存/保存方法 |
Store at -20℃
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| 参考文献 | |
| 参考文献 |
1.Vázquez, M.J.,Leavens, W.,Liu, R., et al. Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the β-ketoacyl reductase reaction. FEBS Journal 275(7), 1556-1567 (2008).
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分子结构图
