HHS-0701

HHS-0701CAS号: 2851993-91-2分子式: C20H20N4O3S分子量: 396.46描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)

产品描述
描述
HHS-0701 is a sulfur-triazole exchange (SuTEx) ligand. HHS-0701 is a potent inhibitor of tyrosine-reactive prostaglandin reductase 2 (PTGR2). HHS-0701 can block PTGR2 metabolism of the lipid substrate 15-Keto-PGE2.
纯度
97%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:3.96 mg/mL (10 mM)
生物活性
In vitro(体外研究)
HHS-0701 (0.1, 0.25, 0.5, 1, 2.5, 5, 10, 25 μ M; 2 hours) resulted in concentration dependent probe labeling blockade when processing recombinant PTGR2 overexpressing HEK293T cells[1].