KDU691

KDU691 CAS号: 1513879-19-0分子式: C22H18CIN5O2分子量: 419.86描述纯度储存/保存方法可溶性/溶解性靶点In vivo(体内研究)

产品描述
描述

 KDU691 是一个 PI4K 抑制剂。

纯度
≥98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO :150mg/mL
生物活性
靶点
PI4K
In vivo(体内研究)
During the 5 days of dosing, no major weight changes are observed in the animals that receive KDU691 as prophylactic treatment (group 691-proph). From the fourth day of dosing, the animals that are treated with KDU691 show a transient yellow skin color. The KDU691 radical-cure group (group 691-RC) becomes blood-stage positive again at 31.8±0.5 days p.i. (range, 31 to 32 days). Clinical chemistry analysis of the group 691-RC monkeys reveals that bilirubin levels accumulate during the 5-day radical-cure treatment with KDU691.

分子结构图

KDU691