ICA 069673CAS号: 582323-16-8分子式: C11H6ClF2N3O分子量: 269.63描述应用储存/保存方法形态别名密度熔点沸点折射率IC50PK值可溶性/溶解性MDLPubChem CID
产品描述 | |
描述 |
ICA 069673 is a potassium channel opener with selective action for KCNQ2 and KCNQ3 (EC50=0.69 μM). No meeasurable activity was displayed over a variety of cardiac ion channels.
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应用 |
A selective activator of the KCNQ2/Q3 potassium channel
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储存/保存方法 |
Store at room temperature
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形态 |
Solid
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基本信息 | |
别名 |
N-(2-Chloro-5-pyrimidinyl)-3,4-difl uorobenzamide
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密度 |
~1.5 g/cm3 (Predicted)
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熔点 |
167.15° C (Predicted)
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沸点 |
~358.9° C at 760 mmHg (Predicted)
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折射率 |
n20D 1.63 (Predicted)
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IC50 |
Voltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3): EC5050 = 0.69 µM (human); HERG: IC50 >30 µM (human); Na+ CP type Vα: IC50 >30 µM (human)
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PK值 |
pKa: 9.47 (Predicted)
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可溶性/溶解性 |
Soluble in DMSO (100 mM), and ethanol (25 mM).
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MDL |
MFCD20926351
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PubChem CID |
10149311
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