Mouse anti-MC1R Monoclonal Antibody(Center)(578CT6.2.3)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法存储溶液研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Mouse Monoclonal Antibody (Mab)
|
| 别名 |
MC1R抗体;Melanocyte-stimulating hormone receptor; MSH-R; Melanocortin receptor 1; MC1-R; MC1R; MSHR
|
| 宿主 |
Mouse
|
| 特异性 |
This MC1R antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 205-232 amino acids from the Central region of human MC1R.
|
| 反应种属 |
Human
|
| 应用 |
WB~~1:100~250
|
| 分子量 |
Predicted molecular weight: 35kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
578CT6.2.3
|
| 同种型 |
IgM
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 存储溶液 |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
|
| 研究领域 |
Metabolism;Neuroscience;GPCR Antibodies
|
| 靶标 | |
| 背景说明 |
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
|
| 细胞定位 |
Cell membrane; Multi-pass membrane protein.
|
| UniProt |
Q01726
|
| 参考文献 | |
| 参考文献 |
Demenais, F., et al. J. Natl. Cancer Inst. 102(20):1568-1583(2010)
Strange, R.C., et al. Mult. Scler. 16(9):1109-1116(2010) Ibarrola-Villava, M., et al. Exp. Dermatol. 19(9):836-844(2010) Smith, G., et al. Pharmacogenet. Genomics (2010) In press : Kricker, A., et al. Cancer Causes Control (2010) In press : |
实验结果图
MC1R Antibody (Center)(Cat. #JP100272) western blot analysis in A375 cell line lysates (35μg/lane).This demonstrates the MC1R antibody detected the MC1R protein (arrow).