PF-04745637CAS号： 1917294-46-2分子式： C27H32ClF3N2O2分子量： 509描述纯度储存/保存方法可溶性/溶解性靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
|
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 可溶性/溶解性 |
DMSO:60 mg/mL (117.88 mM)
|
| 生物活性 | |
| 靶点 |
TRPA1:17 nM
|
| In vivo(体内研究) |
PF-04745637 (topically applied; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin[1].
|