GW 542573X

GW 542573XCAS号: 660846-41-3分子式: C19H28N2O5分子量: 364.44描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)

产品描述
描述
GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of hSK1 from an EC50 (Ca2+) value of 410 nM to 240 nM, which can be used to study neurological disorders.
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:90.0 mg/mL (247.0 mM)
生物活性
In vitro(体外研究)
GW 542573X (100 μM, 200 μM; brain slices from normal rat) was found effective in dose-dependently increasing the interval between seizure-like events.[2]