DS16570511CAS号： 2446154-84-1分子式： C30H25Cl2N3O4分子量： 562.45描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)
| 产品描述 | |
| 描述 |
DS16570511 is a novel cell-permeable inhibitor of the mitochondrial calcium uniporter, which blocks the MCU- or MICU1-dependent increase of Ca 2+ influx [1].
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:124 mg/mL(220.47 mM)
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| 生物活性 | |
| In vitro(体外研究) |
DS16570511 dose-dependently inhibits serum-induced mitochondrial Ca 2+ influx in HEK293A cells with an IC 50 of 7 μM [1]. DS16570511 inhibits Ca 2+ uptake of isolated mitochondria from human cells, rat heart as well as pig heart [1].
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