Mouse anti-RASSF2 Monoclonal Antibody(1509CT269.10.9.29)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Purified Mouse Monoclonal Antibody (Mab)
|
| 别名 |
RASSF2抗体;Ras association domain-containing protein 2; RASSF2; KIAA0168
|
| 宿主 |
Mouse
|
| 特异性 |
This RASSF2 antibody is generated from a mouse immunized with a recombinant protein between 1-326 amino acids from human RASSF2.
|
| 反应种属 |
Human
|
| 应用 |
FC~~1:25
WB~~1:2000 |
| 分子量 |
Predicted molecular weight: 38kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
1509CT269.10.9.29
|
| 同种型 |
IgG2a,κ
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 研究领域 |
Cancer;Signal Transduction
|
| 靶标 | |
| 背景说明 |
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
|
| 细胞定位 |
Nucleus. Cytoplasm. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1
|
| UniProt |
P50749
|
| 参考文献 | |
| 参考文献 |
Burbee D.G.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 3:17-24(1996). Ota T.,et al.Nat. Genet. 36:40-45(2004). Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). |
实验结果图
Anti-RASSF2 Antibody at 1:2000 dilution + Raji whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.