A 77636 hydrochloride is a selective and potent dopamine D₁-like agonist stimulating the release of adenylate cyclase. It has been reported that upon binding to D1DR (dopamine D₁ receptors), A 77636 hydrochloride displays 85% of the intrinsic activity that dopamine provides. Some studies show that A 77636 hydrochloride also increases the release of cortical acetylcholine. A 77636 hydrochloride is an activator of D1DR.

A selective dopamine D₁-like receptor agonist

>98%

Store at 4° C

Solid

220° C

515.3° C at 760 mmHg (Predicted)

n²⁰_D ~1.64 (Predicted)

α20/D -76°, c = 0.93 in methanol

Soluble in water (100 mM), ethanol (100 mM), and DMSO (100 mM).

MFCD03107804

9951033