描述
ProteOn™ XPR36 ProteOn™ XPR36 蛋白质相互作用阵列系统是一种表面等离子体共振(SPR) 光学生物传感器，可提供有关蛋白质相互作用的亲和性、特异性和动力学的实时数据。 通过使用独特的复合式 XPR™ 技术，该系统可以生成一个 6 x 6 阵列的相互作用芯片，能同时分析最多 6 个分析物和 6 个配体之间的相互作用。 ProteOn XPR36 系统可提高实验通量，灵活方便的实验设计为您的研究节省更多的时间：
- 可一次实验，在一块芯片上可分析多达 36 个不同的蛋白相互作用
- 在单个实验中进行完整的动力学分析
- 同时并行测量各种试验条件
- 能高通量地筛选样品
ProteOn XPR36 蛋白质相互作用分析系统包括相互作用分析所需的所有组件： 仪器、ProteOn Manager™ 软件、ProteOn 传感器芯片、缓冲液和检测试剂盒以及实验方案研发试剂盒。
ProteOn Manager™ 软件带有灵活的导向功能，配合进行仪器的控制、实验的建立和数据分析等工作。
主要功能和优点
- 新型 6 × 6 阵列设计
- 实时数据采集
- 对相互作用动力学、结合亲和性和分析物浓度的分析
- 无需放射性或荧光标记
- 集成系统
应用和用途
- 抗体的特征和研发
- 大分子和小分子药品研发
- 蛋白-蛋白相互作用分析
- 蛋白质结构和折叠的分析
* 专利申请中。
Related Technologies
-
Label-Free Biomolecular Interactions -
SPR Assay Development and Experimental Optimization -
Large and Small Molecule Screening by SPR -
Label-Free Interaction Validation and Characterization
Related Products
-
Bio-Plex 200 系统 -
Experion™ 全自动电泳工作站
技术指标
<1.5 RU，20,000–40,000 RU
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相关资料
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Building New Anti-HIV Molecules with Bio-Rad’s ProteOn XPR36 System, Rev A
The ProteOn HTG Sensor Chip: Novel Surface for Stable Capture of Histidine-Tagged Proteins for Protein-Protein Interaction Analysis, Rev A
Guide to SPR Data Processing on the ProteOn XPR36 Protein Interaction Assay System, Rev A
Guide to SPR Data Analysis on the ProteOn XPR36 System, Rev A
ProteOn™ Sensor Chips, Tips and Techniques, Rev A
Attachment of Membrane Protein Interactions Using Lipoparticles Bound to the Surface of the ProteOn XPR36 Sensor Chips, Rev A
Screening and Characterization of Human Immunoglobulin G Binding Peptides Using the ProteOn XPR36 Protein Interaction Array System, Rev A
High-Throughput Profiling of Kinase Inhibitors Selectivity Using the ProteOn™ XPR36 Protein Interaction Array System, Rev A
ProteOn XPR36 Protein Interaction Array System Brochure, Rev D
ProteOn XPR36 Hardware Product Information Sheet, Rev B
ProteOn Manager Software Product Information Sheet, Rev C
ProteOn™ Sensor Chips Product Information Sheet, Rev F
ProteOn Protocol Development Kits Product Information Sheet, Rev B
Protein Interaction Analysis Ordering Information Sheet, Rev E
ProteOn XPR36 Protein Interaction Array System: Regulatory Tools for Drug Development Product Focus, Rev A
Rapid, High-Throughput Screening of Protein Kinase Inhibitors Using the ProteOn XPR36 Protein Interaction Array System, Rev B
Determining the Binding Kinetics of HIV-1 Nucleocapsid Protein to Six Densities of Oligonucleotide Using the ProteOn XPR36 Protein Interaction Array System, Rev A
Antibody Characterization and Development: ProteOn XPR36 Protein Interaction Array System Application Guide, Rev C
Screening, Ranking, and Epitope Mapping of Anti-Human IL-9 Supernatants, Rev A
Rapid Screening and Selection of Optimal Antibody Capturing Agents Using the ProteOn XPR36 Protein Interaction Array System, Rev A
Rapid and Efficient Determination of Kinetic Rate Constants Using the ProteOn XPR36 Protein Interaction Array System, Rev B
Rapid and Detailed Analysis of Multiple Antigen-Antibody Pairs Using the ProteOn XPR36 Protein Interaction Array System, Rev A
Rapid Optimization of Immobilization and Binding Conditions for Kinetic Analysis of Protein-Protein Interactions Using the ProteOn™ XPR36 Protein Interaction Array System, Rev A
Anaylsis of Multiple Protein-Protein Interactions Using the ProteOn XPR36 Protein Interaction Array System, Rev B
Mechanisms of Protein-Protein Binding: Double-Mutant Cycle Analysis Using the ProteOn XPR36 System, Rev A
How to Perform Excluded Volume Correction on the ProteOn XPR36 Protein Interaction System Protocol Guide, Rev C
Rapid Assay Development and Optimization for Small Molecule Drug Discovery, Rev B
Applications of the ProteOn GLH Sensor Chip: Interactions Between Proteins and Small Molecules, Rev A
Applications of the ProteOn NLC Sensor Chip: Antibody-Antigen, DNA-Protein, and Protein-Protein Interactions, Rev B
ProteOn XPR36 Protein Interaction Array System Folder. (Contains bulletins 3172, 5358, 5360, 5367, 5368, 5390, 5404, 5409, 5410, 5413, 5538, and 5465 DVD, depending on availability)
Highly Efficient Lipoparticle Capture and SPR Binding Kinetics of a Membrane Protein Using the ProteOn XPR36 Protein Interaction Array System, Rev A
The ProteOn™ HTE Sensor Chip: Novel Surface for Stable Capture of Histidine-Tagged Proteins for Protein-Small Molecule Interaction Analysis, Rev A
Novel Liposome-Capture Surface Chemistries to Analyze Drug-Lipid Interaction using the ProteOn XPR36 System, Rev A
ProteOn™ XPR36 Experimental Design and Application Guide, Rev B