Gamma-globulins function as part of the immune system in protecting the body against infections. IgE can be elevated in various allergic diseases as well as myeloma.
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(MW: 150Kd-900Kd) gamma-globulins that function as part of the immune system in protecting the body against infections. They occur in humans as five different classes including IgG, IgM, IgA, IgE, and IgD and are synthesized by the B lymphocytes. Diseases resulting from deficiencies of the immunoglobulins typically result in recurrent infections and are less severe than the immunodeficiencies due to T cell defects or immunodeficiencies due to defects in both T and B cells. Immunoglobulin deficiencies also are seen in other non-genetic conditions including protein losing enteropathies and the nephrotic syndrome
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