Inhibin A in both males and females inhibits FSH production. It is part of a prenatal screen performed during pregnancy as a marker for Down’s syndrome, but also relevancy in ovarian cancer and male infertility.
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Inhibin A is a dimeric protein consisting of α and β subunits with molecular weight of about 35 kD. It is secreted in females in the ovaries, pituitary gland, placenta and corpus luteum primarily and in males it is secreted from Sertoli cells in the testes.
Inhibin A in both males and females inhibits FSH production. It is part of a prenatal screen performed during pregnancy as a marker for Down’s syndrome, but also relevancy in ovarian cancer and male infertility.