GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity.

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

GV196771A, developed for the treatment of neuropathic pain, is a potent antagonist of the modulatory glycine site of the N-methyl-D-aspartate receptor (NMDA receptor). It exhibits low oral bioavailability in rats and mice, with a bioavailability of less than 10% and a plasma clearance of approximately 2 mL/min/kg[1].