MEK1抗体;Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K1; MEK1; PRKMK1

Rabbit

This MEK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-227 amino acids from the Central region of human MEK1.

Human, Mouse, Rat

Drosophila, C.Elegans, Hamster, Rabbit, Rat, Xenopus, Chicken

WB

Predicted molecular weight: 43kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Polyclonal Antibody

Rabbit Ig

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

The protein encoded by this gene is a member of the dual
specificity protein kinase family, which acts as a
mitogen-activated protein (MAP) kinase kinase. MAP kinases, also
known as extracellular signal-regulated kinases (ERKs), act as an
integration point for multiple biochemical signals. This protein
kinase lies upstream of MAP kinases and stimulates the enzymatic
activity of MAP kinases upon wide variety of extra- and
intracellular signals. As an essential component of MAP kinase
signal transduction pathway, this kinase is involved in many
cellular processes such as proliferation, differentiation,
transcription regulation and development.

Liang, Q., et al. J. Immunol. 185(10):5704-5713(2010)
Yokoyama, T., et al. Blood 116(15):2768-2775(2010)
Klemke, M., et al. EMBO J. 29(17):2915-2929(2010)
Shang, C., et al. Med. Sci. Monit. 16 (6), BR168-BR173 (2010) :
Sasaki, H., et al. J Thorac Oncol 5(皪Ỵ皫㟹皩腙癹